All You Need To Know About Adrafinil And PTSD

Adrafinil And PTSD
Written by Nancy

Although researchers have recently discovered the benefits of nootropics, they have been used for medicinal purposes by the Chinese for thousands of years.

Nootropics are a class of chemicals that are used to improve cognitive functions and treat various neurodegenerative diseases, as well as mental illnesses.

They can be either natural or synthetic. Nootropics like adrafinil have been gaining popularity because of their numerous benefits for the human brain.

Psychological Anatomy of PTSD

Studies show that at least 70% of adults in the U.S. have experienced some kind of traumatic event at least once in their lives. Out of this 70 %, 20% develop Post-Traumatic Stress Disorder (PTSD).

According to the same report, 5% of American adults (Around 13 million people) have PTSD and women are twice as likely to develop PTSD than men.

Studies show that by the time a person is in their late 20s, the gray matter in their brain begins to change. For women, menopause can lead to low production of estrogen, which can affect the neurons of the brain, making them more vulnerable to depression.

Low estrogen levels also affect the brain’s ability to function properly.

It’s not easy living with the disorder, whether it’s yourself, or someone you love who is the victim.

What makes the disorder extremely difficult to live with is the fact that it affects the emotional and physical well-being of an individual. The individual is almost always in a state of helplessness, feeling terrified and going into shock whenever a situation occurs that triggers them.

The amygdala region of the brain is responsible for controlling emotions. The brain of an individual with PTSD is different because there is more activity in their amygdala region when they experience stress or anxiety than the average person.

When an individual with PTSD encounters danger or are put in a threatening situation, the amygdala sends a “flight or fight” signal to the central system of the brain. Except, that “danger” may not even exist!

For example, an individual with PTSD is visiting the zoo with their family when they see a lion. The amygdala region automatically sends a “flight or fight” signal to the brain, even though the lion is inside a cage.

For normal people, this wouldn’t be a problem. But for someone with PTSD, it’s a matter of life and death.

Adrafinil and PTSD

A group of 471 adults with depression were administered adrafinil and showed significant signs of improvement. In another study, 70 patients were administered an anti-depressant (clomipramine) and another group was administered adrafinil.


The group that was administered the anti-depressant reported suffering frequent side effects. But adrafinil was well-tolerated.


Adrafinil helps improve cognitive functions by encouraging the release of neurotransmitters in the brain. Neurotransmitters like GABA, serotonin, and dopamine create feelings of happiness and help the brain relax in stressful situations.


In conclusion, adrafinil has the potential to treat individuals with various mental illnesses and disorders, and help them lead healthier, happier lives.


*Note: Please consult your doctor before self-administering adrafinil. While the nootropic does not have side effects, the dosage needs to be adjusted properly and different patients react differently to the drug.

Looking for nootropics online? BlueBrainBoost offers a comprehensive list of nootropics and brain supplements to improve cognitive performance. Browse through their collection to learn more.

About the author



I’m Nancy and no, I didn’t always look like I do in that picture on the right. My foray into health and fitness began as a brace-faced, 16 year-old who was too afraid to wear a two-piece at the beach because I felt my body paled in comparison to my much more toned friends.

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